Create a data table of patients to model.
create_patients(n, female_prop = 0.48, age_mean = 70.39, age_sd = 11.68, mutation_prob = 0.52)
| n | Number of patients to model. |
|---|---|
| female_prop | The proportion of patients that are female. |
| age_mean | Mean age. Based on sources cited in |
| age_sd | Standard deviation of age. Based on sources cited in |
| mutation_prob | The probability of a T790M mutation. The default value is based on Table 3 from the article by Ma et al. cited below. |
An object of class "patients", which is a data.table
containing each modeled patient. Columns are:
An integer from 1 to n denoting a unique patient.
1 if a patient has a T790M mutation and 0 otherwise.
1 if a patient is female and 0 otherwise.
Ma C, Wei S, Song Y. T790M and acquired resistance of EGFR TKI: a literature review of clinical reports. Journal of thoracic disease. 2011 Mar;3(1):10.
https://seer.cancer.gov/csr/1975_2015/results_merged/topic_age_dist.pdf
create_patients(n = 10)#> patient_id female age mutation #> 1: 1 1 59.36289 0 #> 2: 2 1 49.58720 1 #> 3: 3 1 62.02643 0 #> 4: 4 1 81.03140 0 #> 5: 5 0 61.37080 1 #> 6: 6 0 61.25533 1 #> 7: 7 1 65.34196 0 #> 8: 8 1 62.59284 0 #> 9: 9 0 86.61943 1 #> 10: 10 0 81.04069 0