ttd.all
, ttd.da
, and ttd.eular
are lists of lists containing parameters
from statistical models of time to treatment discontinuation. ttd.all
contains
parameters representative of all patients, ttd.da
contains covariates for disease
activity level (moderate, high), and ttd.eular
is stratified by EULAR response
(moderate, good).
ttd.eular ttd.da ttd.all
A list as described in sample_pars
Stevenson, Matt, et al. "Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation." Health Technology Assessment 20.35 (2016): 1-610.
Zhang, Jie, et al. "Thresholds in disease activity for switching biologics in rheumatoid arthritis patients: experience from a large US cohort." Arthritis care & research 63.12 (2011): 1672-1679.
Guyot, Patricia, et al. "Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves." BMC medical research methodology 12.1 (2012): 9.
Models were fit using flexsurv. Survival curves are based on analyses of reconstructed individual patient data.